Lymphoedema Evidence Library
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Compression

Compression: bandaging, garments, wraps and pneumatic devices

29 sources
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Evidence in one minute

Industry note: almost every compression guidance document held is manufacturer-sponsored (Sigvaris, BSN, Lohmann & Rauscher, medi, Essity, Activa, Haddenham, Juzo).

Update 2026-10-08 — downloaded evidence

  • Prevention (revised 2026-10-08): a sleeve for 4–9% subclinical swelling was not shown to prevent BCRL (PLACE, inconclusive, low certainty); CALGB 70305 did not test prophylactic compression (activity-only sleeve). BIS-triggered sleeves led to less tape-defined chronic BCRL than tape-triggered sleeves (PREVENT, low certainty). Ridner 2022 Paskett 2021 · Bundred 2023 · Ridner 2019
  • IPC: meta-analysis of 14 RCTs (many Chinese) — RR 0.36 for developing BCRL with early low-pressure IPC; little effect in established lymphoedema. Very low certainty (revised 2026-10-08: 5 small prevention trials, contradictory search dates, a subgroup estimate outside its own CI). Su 2025

Appraisal update 2026-10-09

  • Manufacturer-linked material (BSN/JOBST leaflet, Wounds UK quick guides, Charles 2013 SSI article) is accurate on principles but brand-led; cite the ILF/ISL documents for recommendations. The LIPLEG critique arguing that compression was “underrepresented” was translated with compression-industry funding. Wounds UK / BSN medical unknown · Charles 2013 · Bertsch 2025

How the evidence points

HighMod.LowV. lowNone
Positive00120
Null or negative00200

Sources on this page with a comparison, by the result of their primary outcome and the GRADE certainty of their main finding (Mod. = Moderate, V. low = Very low, None = not graded). Context sources are not counted. How direction is decided.

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